Title:
予後および治療標的として乳癌で発現される遺伝子
Document Type and Number:
Japanese Patent JP2005512510
Kind Code:
A
Abstract:
Methods are disclosed for, determining the endocrine responsiveness of breast carcinoma and treating and monitoring the progression of breast carcinoma based on genes which are differentially expressed in breast tumors. Also disclosed are methods for identifying agents useful in the treatment of breast carcinoma, methods for monitoring the efficacy of a treatment for breast carcinoma, methods for inhibiting the proliferation of a breast carcinoma, and breast-specific vectors including the promoters of the disclosed genes.
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Inventors:
Marlene Michel Dressman
Christian Nikola Lovedan
Michael Polymeropulos
Christian Nikola Lovedan
Michael Polymeropulos
Application Number:
JP2002589720A
Publication Date:
May 12, 2005
Filing Date:
April 11, 2002
Export Citation:
Assignee:
NOVARTIS AG
International Classes:
A61K39/395; A61K45/00; A61K48/00; A61P35/00; C12N15/09; C12N15/861; C12Q1/68; G01N33/574; C12Q1/6809; C12Q1/6886; (IPC1-7): C12N15/09; A61K39/395; A61K45/00; A61K48/00; A61P35/00; C12Q1/68; G01N33/574
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima