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Title:
イヌにおける肝臓の銅蓄積についての遺伝子検査
Document Type and Number:
Japanese Patent JP6728442
Kind Code:
B2
Abstract:
The present invention provides a method of testing a dog to determine the susceptibility of the dog to liver copper accumulation, comprising detecting in a sample the presence or absence in the genome of the dog of one or more polymorphisms selected from:(a) Chr22_3167534 (SEQ ID NO: 144), Chr22_3135144 (SEQ ID NO: 145), Chr20_55461150 (SEQ ID NO: 146), ChrX_120879711 (SEQ ID NO: 147), Chr19_6078084 (SEQ ID NO: 148), Chr15_62625262 (SEQ ID NO: 149), Chr14_39437543 (SEQ ID NO: 150), Chr15_62625024 (SEQ ID NO: 151), Chr3_86838677 (SEQ ID NO: 152), Chr24_4011833 (SEQ ID NO: 153), Chr18_60812198 (SEQ ID NO: 154), Chr10_65209946 (SEQ ID NO: 155), and the CGCCCC repeat at chromosome location 22:3135287;(b) one or more polymorphisms in linkage disequilibrium with a said polymorphism (a); and/or(c) Chr32_38904515 (SEQ ID NO: 156), Chr8_4892743 (SEQ ID NO: 157) and Chr8_4880518 (SEQ ID NO: 158).

Inventors:
Martin, Alan James
Johns, Paul Grin
Watson, Adrian
Rochuzen, Jean
Feeten, Hill
League Water, Peter Antonius Joseph
Application Number:
JP2019088519A
Publication Date:
July 22, 2020
Filing Date:
May 08, 2019
Export Citation:
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Assignee:
MARS INCORPORATED
International Classes:
C12Q1/68; G16B20/10; G16B20/20; G16B20/40
Domestic Patent References:
JP2011501658A
Foreign References:
WO2010038032A1
WO2010116137A1
WO2003033734A2
Other References:
CORONADO V A ET AL,THE VETERINARY JOURNAL,vol. 177, no. 2(2008),p.293-296
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Yasuhito Suzuki