Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
GLUCOHYDANTOIN DERIVATIVE, ULTRAVIOLET ABSORBENT AND SKIN PREPARATION FOR EXTERNAL USE
Document Type and Number:
Japanese Patent JPH08127589
Kind Code:
A
Abstract:

PURPOSE: To obtain the subject new derivative which is a specific glucohydantoin derivative, water-soluble and has properties absorbing ultraviolet rays in VV-A region and useful for cosmetics, quasi-drugs, etc., as an ultraviolet absorbent, a skin preparation for external use obtained by blending the absorbent.

CONSTITUTION: This hydantoin derivative is expressed by formula I [A is a residue after removal of one hydroxyl group from a sugar; R is a 1-20C alkyl; X is a 1-8C alkyl or a 1-8C alkoxy; (a) is an integer of 0-4) and is excellent in solubility to water and has properties absorbing ultraviolet rays in VV-A region and is useful for preparations for external use such as cosmetics or quasi-drugs, etc., as an ultraviolet absorbing agent and a skin preparation for external use by blending the agent. The hydantoin derivative is obtained by reacting a hydroxybenzaldehyde derivative of formula II with a hydantoin of formula III in the presence of an amino acid, reacting the reactional product with an acrylic acid ester in the presence of a base in a solvent to afford a compound of formula IV and then reacting the compound of formula IV with a halogenated sugar.


Inventors:
NAKATSUGAWA HIROKO
NISHIO HIROYUKI
Application Number:
JP1994000289302
Publication Date:
May 21, 1996
Filing Date:
October 27, 1994
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
KANEBO LTD
International Classes:
C07H15/203; A61K8/00; A61K8/60; A61Q17/04; C09K3/00; (IPC1-7): C07H15/203; A61K7/00; A61K7/42; C09K3/00