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Title:
グリシン輸送体-1阻害剤
Document Type and Number:
Japanese Patent JP5179486
Kind Code:
B2
Abstract:
The present invention provides compounds that are glycine transporter 1 (hereinafter referred to as GlyT-1) inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of GlyT1 such as cognitive disorders associated with Schizophrenia, ADHD (attention deficit hyperactivity disorder), MCI (mild cognitive impairment), and the like. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

Inventors:
Hitchi Kotsk, Stephen
Armagier, Albert
Cian, Wen Yuan
Xia, Xiaoyang
Harryd, Scott S
Application Number:
JP2009518233A
Publication Date:
April 10, 2013
Filing Date:
June 26, 2007
Export Citation:
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Assignee:
Amjien Incorporated
International Classes:
C07D241/04; A61K31/495; A61K31/496; A61P25/00; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P27/02; A61P27/16; A61P43/00; C07D295/06; C07D295/14; C07D401/10; C07D409/06; C07D409/10; A61K31/551; C07D241/08; C07D243/08
Domestic Patent References:
JP2000513024A
JP2005513128A
JP2001500107A
Foreign References:
WO2003031435A1
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura