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Title:
GLYCOSIDE-CONTAINING LIPOSOME
Document Type and Number:
Japanese Patent JP2011102321
Kind Code:
A
Abstract:

To provide a medical preparation which can maximize the effect of a cholestanol glycoside useful as an antitumor agent.

There is provided an anticancer agent containing a liposomal glycoside obtained by adding an organic solvent and water to a glycoside expressed by formulas (2) and (3) (wherein G is GlcNAc-Gal-, GlcNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc- or Gal-; and n is an integer of 12-26), a phospholipid and a positive charge donating substance, mixing the mixture, removing the organic solvent and then removing water from the mixture.


Inventors:
YAZAWA SHIN
TAKAI IZUMI
NISHIMURA TOYO
Application Number:
JP2011008898A
Publication Date:
May 26, 2011
Filing Date:
January 19, 2011
Export Citation:
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Assignee:
OTSUKA PHARMA CO LTD
International Classes:
A61K31/7032; A61K9/127; A61K31/7034; A61K31/704; A61K47/18; A61K47/24; A61P35/00; C07H15/10; C07H15/18; C07J17/00
Domestic Patent References:
JPH1160592A1999-03-02
JP2000191685A2000-07-11
JPH03279394A1991-12-10
JPH0193562A1989-04-12
JP2002503685A2002-02-05
JP2000319200A2000-11-21
JP2001354639A2001-12-25
JPH1160592A1999-03-02
JP2000191685A2000-07-11
JPH03279394A1991-12-10
Other References:
JPN6010040384; The Journal of Biological Chemistry Vol.272, No.41, 1997, p.25608-25616
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto