Title:
配糖体含有リポソーム
Document Type and Number:
Japanese Patent JP5295277
Kind Code:
B2
Abstract:
A drug product which can maximize the effect of a cholestanol glycoside useful as an anticancer agent. The present invention provides a liposomal composition containing a glycoside exhibiting antitumor activity, a phospholipid, and a positive-charge-providing substance; the glycoside being composed of GlcNAc-Gal-, GlcNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc-, or Gal- as a sugar moiety, and a hydrophobic compound capable of forming a liposome.
Inventors:
Yazawa Shin
Izumi Takai
Nishimura Toyo
Izumi Takai
Nishimura Toyo
Application Number:
JP2011008898A
Publication Date:
September 18, 2013
Filing Date:
January 19, 2011
Export Citation:
Assignee:
Otsuka Pharmaceutical Co., Ltd.
International Classes:
A61K9/127; A61K31/7032; A61K31/7034; A61K31/704; A61K47/18; A61K47/24; A61P35/00; C07H15/10; C07H15/18; C07J17/00
Domestic Patent References:
JP1093562A | ||||
JP2002503685A | ||||
JP2000319200A | ||||
JP2001354639A | ||||
JP11060592A | ||||
JP2000191685A | ||||
JP3279394A |
Other References:
The Journal of Biological Chemistry,1997年,Vol.272, No.41,p.25608-25616
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
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