Title:
核酸分子の糖修飾用配糖体
Document Type and Number:
Japanese Patent JP5522355
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a glycoside that can more easily introduce a ligand, can carry out the functional modification of a nucleic acid molecule without adversely influencing its function, and can be suitably used in carrying out the sugar modification of a variety of biologically active substances utilizing a solid phase synthesis method.SOLUTION: The glycoside is represented by formula (I) (in the formula, A, B, and Rto Reach represents a functional group or a protected hydroxy group; and a, b, c, m and n each represents a suitable integer). The glycoside can suitably be used for the sugar modification of a nucleic acid by a solid phase synthesis method.
Inventors:
Yukio Nagasaki
Yutaka Ikeda
Yutaka Ikeda
Application Number:
JP2009160887A
Publication Date:
June 18, 2014
Filing Date:
July 07, 2009
Export Citation:
Assignee:
University of Tsukuba
International Classes:
C07H15/18; C12N15/09
Other References:
Synlett,2003年,n9,1331-1333
Tetrahedron,1996年,52,4527-4554
Tetrahedron,1997年,53,5643-5678
ファルマシア,2001年,37,884-888
薬学雑誌,2002年,122,295-307
Tetrahedron Lett.,1988年,29,5743-5744
Tetrahedron,1996年,52,4527-4554
Tetrahedron,1997年,53,5643-5678
ファルマシア,2001年,37,884-888
薬学雑誌,2002年,122,295-307
Tetrahedron Lett.,1988年,29,5743-5744
Attorney, Agent or Firm:
Patent business corporation Odashima patent office