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Title:
GRANULATED PARTICLE, TABLET AND METHOD FOR PRODUCING GRANULATED PARTICLE
Document Type and Number:
Japanese Patent JP2007314529
Kind Code:
A
Abstract:

To provide granulated particles having excellent elution properties of a drug in the body, to provide a tablet and to provide a method for producing the granulated particles.

The granulated particles comprise a sparingly water-soluble drug (A) and a vehicle (B). The granulated particles are characterized in that the volume-average particle diameter of particles of the component (A) and particles of the component (B) is 0.01-35 μm and the granulated particles further contain a water-soluble high polymer and/or a water-swellable high polymer (C) and a surfactant (D).

COPYRIGHT: (C)2008,JPO&INPIT


Inventors:
NISHITO HIDEO
YANASE TOMIYUKI
Application Number:
JP2007120331A
Publication Date:
December 06, 2007
Filing Date:
April 27, 2007
Export Citation:
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Assignee:
LION CORP
International Classes:
A61K9/14; A61K9/20; A61K31/137; A61K31/167; A61K31/192; A61K31/522; A61K31/616; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61P29/00; B01J2/16; B01J2/28
Domestic Patent References:
JPH0366613A1991-03-22
JPH02268117A1990-11-01
JP2002241284A2002-08-28
JP2001335469A2001-12-04
Foreign References:
WO1994008709A11994-04-28
WO2002043704A12002-06-06
Attorney, Agent or Firm:
Masatake Shiga
Tadashi Takahashi
Takashi Watanabe
Masakazu Aoyama
Suzuki Mitsuyoshi
Kazuya Nishi
Yasuhiko Murayama