Title:
増殖因子結合化合物および使用方法
Document Type and Number:
Japanese Patent JP4758359
Kind Code:
B2
Abstract:
Growth factor binding compounds having a plurality of acyclic isophthalic acid groups attached to a non-peptide organic scaffold and pharmaceutical compositions of the same are disclosed. Methods of administering and using the growth factor binding compounds or the growth factor binding compositions are also taught. These novel growth factor binding compounds are useful for treating angiogenesis, excessive cellular proliferation, tumor growth, and a combination thereof as well as inhibiting growth factor binding to cells and phosphorylation.
More Like This:
Inventors:
Cebuti Said M.
Hamilton Andrew Dee.
Jane Rishi
Hamilton Andrew Dee.
Jane Rishi
Application Number:
JP2006551569A
Publication Date:
August 24, 2011
Filing Date:
January 27, 2005
Export Citation:
Assignee:
University of South Florida
Yale University
Yale University
International Classes:
C07C235/56; A61K31/195; A61K31/196; A61K31/216; A61K31/4409; A61K47/48; A61P35/00; A61P35/02; A61P43/00; C07C237/42; C07D213/75
Domestic Patent References:
| JP2005514462A | 2005-05-19 |
Foreign References:
| WO2001070930A2 | 2001-09-27 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi