Title:
グアイアズレン誘導体、がん細胞阻害薬及び前立腺がん細胞阻害薬
Document Type and Number:
Japanese Patent JP6644990
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide: guaiazulene derivatives suitable as cancer cell inhibitors, particularly prostate cancer cell inhibitors; and cancer cell inhibitors, particularly prostate cancer cell inhibitors, containing the same.SOLUTION: The invention relates to guaiazulene derivatives having a structure represented by general formula (1) in the figure, and to cancer cell inhibitors, particularly prostate cancer cell inhibitors, containing the same.SELECTED DRAWING: None
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Inventors:
Toshio Tanaka
Yuhei Nishimura
Yasuto Shimada
Ariyoshi Miko
Kamezawa Makoto
Kimura Takachi
Takahisa Tanaka
Yuhei Nishimura
Yasuto Shimada
Ariyoshi Miko
Kamezawa Makoto
Kimura Takachi
Takahisa Tanaka
Application Number:
JP2016038591A
Publication Date:
February 12, 2020
Filing Date:
March 01, 2016
Export Citation:
Assignee:
Mie University
Konan Kako Co., Ltd.
Konan Kako Co., Ltd.
International Classes:
C07C33/44; A61K31/045; A61K31/12; A61P35/00; C07C49/567
Domestic Patent References:
| JP2001169798A | ||||
| JP59016867A |
Other References:
Anticancer Research ,2006年,Vol.26,pp.1917-1924
In Vivo,2007年,Vol.21,pp.715-720
木村 崇知ら,リパーゼを用いる含フッ素キラルアズレンアルコール類の合成,日本農芸化学会誌,2001年,75巻sup号,151頁,講演番号215a15
Natural Product Research ,英国,2013年,Vol.27,pp.862-868
Journal of Intercultural Ethnopharmacology,2015年,Vol.4,pp.29-33
Anticancer Research ,2003年,Vol.23,pp.4747-4755
Journal of Medicinal Chemistry,1993年,Vol.36,pp.3137-3147
In Vivo,2007年,Vol.21,pp.715-720
木村 崇知ら,リパーゼを用いる含フッ素キラルアズレンアルコール類の合成,日本農芸化学会誌,2001年,75巻sup号,151頁,講演番号215a15
Natural Product Research ,英国,2013年,Vol.27,pp.862-868
Journal of Intercultural Ethnopharmacology,2015年,Vol.4,pp.29-33
Anticancer Research ,2003年,Vol.23,pp.4747-4755
Journal of Medicinal Chemistry,1993年,Vol.36,pp.3137-3147
Attorney, Agent or Firm:
Tomohiro Sakamoto
Naoki Fukumura
Naoki Fukumura