Title:
MC4-Rアゴニストとしてのグアニジノ置換キナゾリノン化合物
Document Type and Number:
Japanese Patent JP2007501861
Kind Code:
A
Abstract:
A variety of small molecule, guanidine-containing molecules capable of acting as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases when administered to subjects. The compounds have the structures VA, VB, VIIA and VIIB where the values of the variables are defined herein.
Inventors:
Voice, Rustham S.
Aureco Chair, Natalia
Chu, daniel
Smith, aaron
Conley, Christopher Earl.
Thomson, Brian Dee.
De Armas Kuntz, Judith
Musso, David Elle.
Barbian, Kevin Kay.
Thomson, Stephan A.
Swain, William Earl.
Du, Keen S.
Shorter, Brian A.
Speak, Jason Dee.
Bishop, Michael Jay.
Aureco Chair, Natalia
Chu, daniel
Smith, aaron
Conley, Christopher Earl.
Thomson, Brian Dee.
De Armas Kuntz, Judith
Musso, David Elle.
Barbian, Kevin Kay.
Thomson, Stephan A.
Swain, William Earl.
Du, Keen S.
Shorter, Brian A.
Speak, Jason Dee.
Bishop, Michael Jay.
Application Number:
JP2006533275A
Publication Date:
February 01, 2007
Filing Date:
May 21, 2004
Export Citation:
Assignee:
Chiron Corporation
GlaxoSmithKline
GlaxoSmithKline
International Classes:
C07D239/90; A61K31/517; A61K31/519; A61K31/525; A61K31/53; A61K31/5377; A61K31/541; A61K31/551; A61P3/04; A61P3/10; A61P43/00; C07D217/24; C07D239/91; C07D239/95; C07D239/96; C07D253/08; C07D401/04; C07D401/06; C07D401/12; C07D401/14; C07D403/04; C07D403/06; C07D403/12; C07D403/14; C07D405/12; C07D413/12; C07D417/04; C07D417/14; C07D471/04; C07D475/02; C07D487/02; C07D487/04
Domestic Patent References:
| JP2005524649A | 2005-08-18 | |||
| JP2005531583A | 2005-10-20 |
Foreign References:
| WO2001004103A1 | 2001-01-18 | |||
| WO2002081443A1 | 2002-10-17 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita