Title:
HMG-COAレダクターゼ阻害剤およびその調製のための方法
Document Type and Number:
Japanese Patent JP2013519666
Kind Code:
A
Abstract:
A compound of Formula (1), is disclosed wherein P1 and P2 are alcohol protecting groups or 1,3-diol protecting group, R is selected from: wherein R4a is selected from alkyl, aryl, arylalkyl and cycloalkyl, Rc is selected from H, alkyl, aryl, alkaoxy, haloalkyl, monohaloalkyloxy, and dihaloalkyloxy, Rd is selected from alkyl, aryl, arylalkyl, CF3, halo and NO2 and X is selected from O, N—H, N-alkyl and S, Ra and Rb are same or different and each represents hydrogen, an alkyl group of 1 to 12 carbon atoms, an aryl group of 6 to 12 carbon atoms, or an aralkyl group of 7 to 12 carbon atoms.
Inventors:
Shri Prakash Dar Divedi
Dimant Jasbhai Patel
Mahesh Largibhai Rupapara
Dimant Jasbhai Patel
Mahesh Largibhai Rupapara
Application Number:
JP2012552524A
Publication Date:
May 30, 2013
Filing Date:
February 23, 2011
Export Citation:
Assignee:
Cadilla Healthcare Limited
International Classes:
C07D239/42; C07D257/04; C07D405/06; C07D405/12; A61K31/505; A61P3/06; A61P43/00
Domestic Patent References:
| JPH1087603A | 1998-04-07 |
Foreign References:
| WO2008044243A2 | 2008-04-17 | |||
| WO2007125547A2 | 2007-11-08 |
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro