HaemophilusinfluenzaeIV型ピリ線毛 - Nationwide Children's Hospital, Incorporated

Title:

HaemophilusinfluenzaeIV型ピリ線毛

Document Type and Number:

Japanese Patent JP5132939

Kind Code:

B2

Abstract:

The invention described herein relates to a Haemophilus influenzae (H. influenzae) regulon encoding type IV pili. In particular, the invention relates to type IV pili from nontypeable H. influenzae (NTHi) and from H. influenzae strains a, b, c, e and f. The invention provides isolated H. influenzae pilus polynucleotides and polypeptides encoded by the polynucleotides as well as polynucleotides and polypeptides encoded by the polynucleotides involved in the assembly/disassembly of the structure. The invention also relates to uses of these polynucleotides and/or polypeptides including methods for eliciting an immune response to H . influenzae and methods of treating and preventing H. influenzae related pathological conditions.

More Like This:

WO/2017/214950	CONSTRUCTION AND APPLICATION OF LENTIVIRAL VECTOR FOR KNOCKING DOWN HUMAN MIRNA-140 EXPRESSION
JP3976610	Methods for identifying CFTR-binding compounds useful for activating chlorine ion conductance in animal cells
JP2015513399	Compositions and Methods for Producing a Surviving Population of T Cells Useful for the Treatment of Cancer

Inventors:

Bakerets, Lauren O.
Manson, Robert S. Jr.

Application Number:

JP2006547336A

Publication Date:

January 30, 2013

Filing Date:

December 21, 2004

Export Citation:

Click for automatic bibliography generation Help

Assignee:

Nationwide Children's Hospital, Incorporated

International Classes:

C12N15/09; A61K31/7088; A61K35/76; A61K39/00; A61K39/02; A61K39/395; A61P11/00; A61P15/00; A61P27/16; A61P31/04; A61P31/16; C07H21/04; C07K14/195; C07K14/285; C07K16/12; C12N15/74; C12Q1/04; C12Q1/68; G01N33/53; G01N33/569

Domestic Patent References:

JP2001521361A

Other References:

Microbiology,1999年,145(2),401-9
Infect. Immun.,1994年,62(5),1710-8
Infect. Immun.,1996年,64(12),5187-92
Vaccine,1997年,15(9),955-61
Infect. Immun.,2002年,70(3),1422-33
Infect. Immun.,2003年 6月,71(6),3454-62
Proc. Natl. Acad. Sci. USA,2002年,99(2),966-71
J. Bacteriol.,1997年,179(15),4815-20
Appl. Environ. Microbiol. ,2002年,68(2),745-55
Science,1995年,269,496-512
Abstr. Gen. Meet. Am. Soc. Microbiol.,2003年,103,D-001

Attorney, Agent or Firm:

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

Previous Patent: JPS5132938

Next Patent: RETAINING WALL