Title:
無毛マウス
Document Type and Number:
Japanese Patent JP3867172
Kind Code:
B2
Abstract:
The invention relates to an atrichia mouse which grows juvenile hair but is deficient in the ability to grow pelage hair and, more particularly, to an atrichia mouse such that the spontaneous prevalence of wet and dry skin lesions is not less than 70% at the 24th week of age, the number of mast cells in the skin is not less than about 50/linear mm at the 24th week of age, and the serum IgE level is not less than about 3500 ng/ml at the 24th week of age. The atrichia mouse of the invention finds application as an animal model of disease for the research and development of therapeutic drugs for dermatitis, among other kinds of drugs.
Inventors:
Taizo Kondo
Toshio Kondo
Yasuhisa Shiomoto
Toshio Kondo
Yasuhisa Shiomoto
Application Number:
JP50779998A
Publication Date:
January 10, 2007
Filing Date:
July 30, 1997
Export Citation:
Assignee:
OTSUKA PHARMACEUTICAL FACTORY,INC.
International Classes:
A01K67/027; C12Q1/02
Domestic Patent References:
| JP8037996A | ||||
| JP4330240A |
Other References:
Clinics in Dermatology(1988),Vol.6,No.4,p.163-168
MOUSE GENOME(1997),Vol.95,p.698-700
MOUSE GENOME(1997),Vol.95,p.698-700
Attorney, Agent or Firm:
Eiji Saegusa
Kakehi Yuro
Takeshi Ohara
Hiroji Nakagawa
Yasumitsu Tate
Kenji Saito
Jun Fujii
Hitoshi Seki
Mutsuko Nakano
Shinsuke Otsuki
Suzuki Katsuto
Kakehi Yuro
Takeshi Ohara
Hiroji Nakagawa
Yasumitsu Tate
Kenji Saito
Jun Fujii
Hitoshi Seki
Mutsuko Nakano
Shinsuke Otsuki
Suzuki Katsuto