Title:
ハプロタイプ推定装置、および、プログラム
Document Type and Number:
Japanese Patent JP5129809
Kind Code:
B2
Abstract:
The present invention calculates a sum of the count numbers for each of the marker sites to obtain a maximum value of the sum of the count numbers, enumerates polymorphic identification characters up to the count numbers of the polymorphic nucleotides, permutates the enumerated polymorphic identification characters so as to create any character string that has copy units of which the number equals the maximum value, divides the character string into two by the copy unit to store the divided strings as a combination of the haplotype character strings, calculates the number of identical haplotype character strings in the group, obtains a frequency of the haplotype character string in the group, and estimates the combination of the haplotype character strings (representing haplotypes) of each individual of which frequency satisfying a predetermined condition.
More Like This:
Inventors:
Mamoru Kato
Application Number:
JP2009512892A
Publication Date:
January 30, 2013
Filing Date:
February 28, 2008
Export Citation:
Assignee:
RIKEN
International Classes:
G16B20/10; C12M1/00
Domestic Patent References:
| JP2004192018A | 2004-07-08 |
Other References:
JPN6012056783; Ｏｇｉｎｏ， Ｓ．: 'Ｎｅｗ ｉｎｓｉｇｈｔｓ ｏｎ ｔｈｅ ｅｖｏｌｕｔｉｏｎ ｏｆ ｔｈｅ ＳＭＮ１ ａｎｄ ＳＭＮ２ ｒｅｇｉｏｎ： ｓｉｍｕｌａｔｉｏｎ ａｎｄ ｍｅｔａ-ａｎａｌｙｓｉｓ ｆｏｒ ａｌｌｅｌｅ ａ' Ｅｕｒｏｐｅａｎ Ｊｏｕｒｎａｌ ｏｆ Ｈｕｍａｎ Ｇｅｎｅｔｉｃｓ Ｖｏｌ．１２, 2004, ｐ．１０１５-１０２３
JPN6012056784; Ｒｅｄｏｎ， Ｒ．: 'Ｇｌｏｂａｌ ｖａｒｉａｔｉｏｎ ｉｎ ｃｏｐｙ ｎｕｍｂｅｒ ｉｎ ｔｈｅ ｈｕｍａｎ ｇｅｎｏｍｅ' Ｎａｔｕｒｅ Ｖｏｌ．４４４, 20061123, ｐ．４４４-４５４
JPN6012056784; Ｒｅｄｏｎ， Ｒ．: 'Ｇｌｏｂａｌ ｖａｒｉａｔｉｏｎ ｉｎ ｃｏｐｙ ｎｕｍｂｅｒ ｉｎ ｔｈｅ ｈｕｍａｎ ｇｅｎｏｍｅ' Ｎａｔｕｒｅ Ｖｏｌ．４４４, 20061123, ｐ．４４４-４５４
Attorney, Agent or Firm:
Hiroaki Sakai