Title:
Ｂ型肝炎ウイルスコアタンパク質モジュレーター
Document Type and Number:
Japanese Patent JP7023838
Kind Code:
B2
Abstract:
The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.
Inventors:
Turner, William
Arnold, Lee Daniel
Marg, Hans
Re, repin
Bresh, Mark
Haider, Simon
Francis, Samsung
Arnold, Lee Daniel
Marg, Hans
Re, repin
Bresh, Mark
Haider, Simon
Francis, Samsung
Application Number:
JP2018513782A
Publication Date:
March 31, 2022
Filing Date:
September 15, 2016
Export Citation:
Assignee:
Assembly Biosciences, Incorporated
Indiana University Research and Technology Corporation
Indiana University Research and Technology Corporation
International Classes:
C07D417/12; A61K31/55; A61K31/551; A61K31/553; A61K31/554; A61K38/02; A61K39/29; A61K45/00; A61K48/00; A61P1/16; A61P31/20; A61P43/00; C07D417/14; C07D453/02; C07D471/04
Domestic Patent References:
| JP6602311B2 | ||||
| JP2018531921A | ||||
| JP2018531919A |
Foreign References:
| WO2015017412A1 | ||||
| US20070105835 | ||||
| WO2013006394A1 |
Other References:
XIAO, J et al.,Discovery, Optimization, and Characterization of Novel D2 Dopamine Receptor Selective Antagonists,Journal of Medicinal Chemistry,2014年,Vol. 57,pp. 3450-3463
HALL, PR et al.,Small molecule inhibitors of hantavirus infection,Bioorganic & Medicinal Chemistry Letters,2010年,Vol. 20,pp. 7085-7091
HALL, PR et al.,Small molecule inhibitors of hantavirus infection,Bioorganic & Medicinal Chemistry Letters,2010年,Vol. 20,pp. 7085-7091
Attorney, Agent or Firm:
Shusaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto