Title:
ヘテロ6員環化合物及びその用途
Document Type and Number:
Japanese Patent JP5014978
Kind Code:
B2
Abstract:
A compound represented by the general formula (I) or a salt thereof:
[T represents oxygen atom and the like; V represents CH 2 and the like; R O1 to R O4 represent hydrogen atom and the like; A represents a linear alkylene group or linear alkenylene group having 2 to 8 carbon atoms and the like; D represents carboxyl group and the like; X represents ethylene group, trimethylene group and the like; E represents -CH(OH)- group and the like; and W represent -U 1 -(R W1 )(R W2 )-U 2 -U 3 group (U 1 represents a single bond, an alkylene group having 1 to 4 carbon atoms and the like; R W1 and R W2 represent hydrogen atom and the like; U 2 represents a single bond, an alkylene group having 1 to 4 carbon atoms and the like; and U 3 represent an alkyl group having 1 to 8 carbon atoms and the like), or a residue of a carbon ring or heterocyclic compound], which can be utilized as an active ingredient of medicaments effective for prophylactic and/or therapeutic treatment of skeletal diseases such as osteoporosis and fracture, glaucoma, ulcerative colitis and the like.
Inventors:
Motoshi Masada
Toshinori Ishizuya
Toshinori Ishizuya
Application Number:
JP2007500527A
Publication Date:
August 29, 2012
Filing Date:
January 25, 2006
Export Citation:
Assignee:
Asahi Kasei Pharma Co., Ltd.
International Classes:
C07D237/04; A61K31/50; A61K31/501; A61K31/5395; A61K31/549; A61P1/02; A61P1/04; A61P3/14; A61P19/02; A61P19/08; A61P19/10; A61P27/06; A61P29/00; A61P35/00; A61P35/04; A61P41/00; A61P43/00; C07D273/04; C07D285/16; C07D403/06; C07D405/06; C07D409/06
Foreign References:
| WO2004085430A1 | 2004-10-07 | |||
| WO2003035064A1 | 2003-05-01 | |||
| WO2004063158A1 | 2004-07-29 | |||
| EP0299449A2 | 1989-01-18 |
Attorney, Agent or Firm:
Patent Service Corporation Patent Office Sykes