Title:
ヘテロアリール化合物及びその使用
Document Type and Number:
Japanese Patent JP7293343
Kind Code:
B2
Abstract:
Described herein are compounds of formula (I), and pharmaceutically acceptable salts, solvates, hydrates, isotopically labeled derivatives and radiolabeled derivative thereof, and pharmaceutical compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for detecting and imaging Tau aggregates in the brain for detection of Alzheimer's disease (AD) in a subject.
Inventors:
Ming-Kwai Giang
Paul Tempest
Paul Tempest
Application Number:
JP2021512993A
Publication Date:
June 19, 2023
Filing Date:
May 09, 2019
Export Citation:
Assignee:
Appinoia Therapeutics Limited
International Classes:
C07D277/66; A61K49/00; A61K51/04; C07D401/10; C07D413/10; C07D417/10; C07D417/14; C07D471/04; C07D495/04; C07D498/04; G01N33/68; G01T1/161
Domestic Patent References:
| JP2018456A | ||||
| JP61145285A | ||||
| JP2005514382A | ||||
| JP2010519334A | ||||
| JP2012521988A | ||||
| JP2017521387A | ||||
| JP2012502966A | ||||
| JP3217459A |
Foreign References:
| WO2007034282A2 | ||||
| WO2017108282A1 | ||||
| WO2014097474A1 | ||||
| WO2018055316A1 | ||||
| WO2011045415A2 | ||||
| US20170189566 |
Attorney, Agent or Firm:
Takaharu Fujita
Miki Kawakami
Rie Kawai
Miki Kawakami
Rie Kawai