Title:
ＦＧＦＲ４阻害剤としてのヘテロ環式化合物
Document Type and Number:
Japanese Patent JP7008064
Kind Code:
B2
Abstract:
The present invention provides a heterocyclic compound which is an inhibitor of FGFR4 (fibroblast growth factor receptor 4). Specifically, the present invention provides a compound represented by the following formula (I), including an isomer (enantiomer or diastereomer) which may be present, or a pharmaceutically acceptable salt thereof, prodrugs, deuterated derivatives, hydrates, solvates.The definition of each group in the formula (I) is as described in the specification. The compounds of the present invention has FGFR4 inhibitory activity and can be used for the prevention or treatment of diseases associated with FGFR4 activity or expression, and can also be used in combination with other drugs for the treatment of various related diseases.
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Inventors:
Zhang Hanjo
Liu Sebong
Kano Koyo
Liu Sebong
Kano Koyo
Application Number:
JP2019514174A
Publication Date:
January 25, 2022
Filing Date:
May 27, 2017
Export Citation:
Assignee:
Hangzhou Eisou Pharmaceutical Technology Co., Ltd.
International Classes:
C07D471/04; A61K31/497; A61K31/4985; A61K31/551; A61P35/00; A61P43/00; C07D519/00
Domestic Patent References:
| JP2013542966A |
Foreign References:
| WO2015059668A1 | ||||
| WO2011097594A1 | ||||
| WO2015095445A1 | ||||
| WO2017198149A1 | ||||
| US20160075708 |
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office