Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
HETEROCYCLIC COMPOUND, ITS PRODUCTION, USE AND SYNTHETIC INTERMEDIATE
Document Type and Number:
Japanese Patent JP3462234
Kind Code:
B2
Abstract:

PURPOSE: To obtain a new heterocyclic compound, having excellent choline esterase inhibiting activity and antidepressant action and useful as a therapeutic or a preventing agent for senile dementia.
CONSTITUTION: The compound of formula I (tring A is benzene ring; ring B is heterocyclic ring containing ≥2 hetero-atoms; R1 is H or hydrocarbon group; Y is substituted amino or substituted nitrogen-containing saturated heterocyclic group; n is 1-10), e.g. 1-[4-(4-methoxyphenylmethyl)-2,3,4,5-tetrahydro-1,4- benzoxazepin-7-yl]-3-[1-(phenylmethyl)piperidin-4-yl]-1-propanone dihydrochloride. The compound of formula I is obtained by reacting a compound of formula II with a compound of formula III (Z1 is releasable group).


Inventors:
Yoshikazu Goto
Masaomi Miyamoto
Yuji Ishihara
Application Number:
JP11914293A
Publication Date:
November 05, 2003
Filing Date:
April 21, 1993
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
Takeda GmbH
International Classes:
A61K31/39; A61K31/42; A61K31/423; A61K31/445; A61K31/495; A61K31/496; A61K31/505; A61K31/535; A61K31/536; A61K31/5377; A61K31/538; A61K31/54; A61K31/5415; A61K31/55; A61K31/554; A61P25/28; A61P43/00; C07D241/42; C07D243/10; C07D243/12; C07D245/06; C07D263/56; C07D265/16; C07D265/36; C07D267/06; C07D267/14; C07D267/22; C07D273/01; C07D273/06; C07D279/08; C07D279/16; C07D281/10; C07D413/06; C07D413/14; (IPC1-7): C07D263/56; A61K31/39; A61K31/42; A61K31/445; A61K31/495; A61K31/505; A61K31/535; A61K31/54; A61K31/55; A61P25/28; A61P43/00; C07D241/42; C07D243/10; C07D243/12; C07D245/06; C07D265/16; C07D265/36; C07D267/06; C07D267/14; C07D267/22; C07D273/01; C07D273/06; C07D279/08; C07D279/16; C07D281/10; C07D413/06; C07D413/14
Domestic Patent References:
JP60193975A
JP6479151A
Attorney, Agent or Firm:
Mitsuo Kuwata