酵素DPP-IVのインヒビターである複素環式化合物

Title:

酵素DPP-IVのインヒビターである複素環式化合物

Document Type and Number:

Japanese Patent JP2004502690

Kind Code:

A

Abstract:

The present invention relates to therapeutically active and selective inhibitors of the enzyme DPP-IV, which are of formula I wherein each n is one or two independently and R¹, R², R³, R⁶, R⁷, R⁹, and R¹⁰are defined herein. The present invention also relates to pharmaceutical compositions comprising the compounds of formula I and the use of the compounds for treating diseases that are associated with proteins that are subject to inactivation by DPP-IV, such as type-2 diabetes and obesity.

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Inventors:

Canstrup, Anders Benz
Christiansen, Lycee Brown
Lundbeck, Yane Marie
Sams, Christian Kay.
Christiansen, Maritt

Application Number:

JP2002507812A

Publication Date:

January 29, 2004

Filing Date:

July 04, 2001

Export Citation:

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Assignee:

NOVO NORDISK AKTIE SELSXAB

International Classes:

A61K31/522; A61K31/551; A61P3/04; A61P3/10; A61P43/00; C07D473/04; C07D473/06; C07D473/08; C07D519/00; (IPC1-7): C07D473/04; A61K31/522; A61K31/551; A61P3/04; A61P3/10; A61P43/00; C07D473/06; C07D473/08; C07D519/00

Attorney, Agent or Firm:

Takashi Ishida
Jun Tsuruta
Fukumoto product
Masaya Nishiyama
Higuchi Souji

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