Title:
p38の複素環式インヒビター
Document Type and Number:
Japanese Patent JP4704560
Kind Code:
B2
Abstract:
The present invention relates to inhibitors of p38, a mammalian protein kinase involved in cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders.
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Inventors:
Salitaro, Francesco
Garlo, Vincent
Beron, stephen
Bemis, Guy
John Cochrane
Garlo, Vincent
Beron, stephen
Bemis, Guy
John Cochrane
Application Number:
JP2000548306A
Publication Date:
June 15, 2011
Filing Date:
May 11, 1999
Export Citation:
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
A61K31/17; C07D213/75; A61K31/435; A61K31/44; A61K31/4418; A61K31/4427; A61K31/4433; A61K31/4439; A61K31/444; A61K31/4545; A61K31/496; A61K31/5377; A61K31/551; A61P1/04; A61P1/16; A61P1/18; A61P3/10; A61P5/14; A61P7/02; A61P7/04; A61P7/06; A61P9/00; A61P9/02; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P19/08; A61P19/10; A61P21/04; A61P25/00; A61P25/04; A61P25/16; A61P25/28; A61P29/00; A61P31/00; A61P31/04; A61P31/12; A61P31/18; A61P35/00; A61P35/02; A61P37/06; A61P37/08; A61P43/00; C04B35/01; C07C275/32; C07D213/00; C07D213/56; C07D213/73; C07D213/74; C07D401/06; C07D401/12; G02B6/02; G02B6/12; C07D
Foreign References:
| WO1998052937A1 | ||||
| WO1998027098A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita