Title:
疾患を治療するためのＨＩＦ活性の複素環式修飾物質
Document Type and Number:
Japanese Patent JP6453218
Kind Code:
B2
Abstract:
The present invention relates to compounds and methods which may be useful as inhibitors of HIF pathway activity for the treatment or prevention of cancer and other hypoxia-mediated diseases.
Inventors:
Jones philippe
Di Francesco Maria Emilia
Petrocchi Alessia
Carol Christopher El.
Marstsalek Joe
Chaco Barbara
Johnson Ryan
Serov Jay
Di Francesco Maria Emilia
Petrocchi Alessia
Carol Christopher El.
Marstsalek Joe
Chaco Barbara
Johnson Ryan
Serov Jay
Application Number:
JP2015528678A
Publication Date:
January 16, 2019
Filing Date:
August 23, 2013
Export Citation:
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
International Classes:
C07D413/04; A61K31/4245; A61K31/427; A61K31/437; A61K31/4439; A61K31/454; A61K31/4545; A61K31/4709; A61K31/496; A61K31/497; A61K31/506; A61K31/519; A61K31/5377; A61K31/541; A61K45/00; A61P35/00; A61P35/02; A61P35/04; C07D405/14; C07D413/14; C07D417/04; C07D417/14; C07D471/04
Domestic Patent References:
| JP2008541014A | ||||
| JP2010531835A | ||||
| JP2012508703A | ||||
| JP2012508702A | ||||
| JP2010527378A |
Foreign References:
| WO2011006903A1 | ||||
| WO2010054764A1 |
Other References:
European Journal of Medicinal Chemistry,1993年,28(7-8),p.569-576
Bioorganic & Medicinal Chemistry Letters,2011年,21(6),p.1621-1625
Bioorganic & Medicinal Chemistry Letters,2011年,21(6),p.1621-1625
Attorney, Agent or Firm:
Masahiro Nanjo
Ayako Seta
Koichiro Inami
Hidetoshi Hara
Ayako Seta
Koichiro Inami
Hidetoshi Hara