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Title:
ヘテロ機能性の粘膜付着性ガレヌス組成物
Document Type and Number:
Japanese Patent JP4083215
Kind Code:
B2
Abstract:
PCT No. PCT/FR95/00417 Sec. 371 Date Dec. 10, 1996 Sec. 102(e) Date Dec. 10, 1996 PCT Filed Mar. 31, 1995 PCT Pub. No. WO95/26713 PCT Pub. Date Oct. 12, 1995A mucoadhesive controlled-release pharmaceutical formulation comprising at least one active principle selected from the group consisting of melatonin and melatonin derivatives, composed of a first layer and a second layer, the first layer being mucoadhesive and permitting a sustained release of the active principle, and the second layer being nonmucoadhesive, and permitting a rapid release of the active principle.

Inventors:
Brome, Norbert Emile
Application Number:
JP52546495A
Publication Date:
April 30, 2008
Filing Date:
March 31, 1995
Export Citation:
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Assignee:
Bioteck Center S.A.
International Classes:
A61K9/20; A61K9/00; A61K31/4045; A61K31/40; A61K31/485; A61K31/52; A61K31/715; A61K47/30; A61P25/20; A61P25/22; A61P25/24; A61P25/26; A61P35/00; A61P43/00
Domestic Patent References:
JP55062012A
Foreign References:
WO1993007870A1
EP0518468A1
Other References:
新・薬剤学総論, 株式会社南江堂, 1987年 4月10日,改訂第3版, p.260, 265-266
Attorney, Agent or Firm:
Yoshio Kawaguchi
Toru Nakamura
Takeshi Funayama
Naoya Fushimi