同一のN末端を有する塩基性繊維芽細胞増殖因子の高レベル発現

Title:

同一のN末端を有する塩基性繊維芽細胞増殖因子の高レベル発現

Document Type and Number:

Japanese Patent JP4031499

Kind Code:

B2

Abstract:

DNA sequences are provided which encode a form of basic fibroblast growth factor lacking one of the alanine residues immediately following the N-terminal methionine residue of the primary translation product. The DNA sequences can be expressed to produce basic fibroblast growth factor having a homogeneous N-terminus.

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Inventors:

Stewart A. Thompson
Judith A. Abraham

Application Number:

JP2005373146A

Publication Date:

January 09, 2008

Filing Date:

December 26, 2005

Export Citation:

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Assignee:

CALIFORNIA BIOTECHNOLOGY INC.

International Classes:

C12N15/09; A61K38/22; A61P3/10; A61P7/02; A61P17/02; A61P19/00; A61P25/00; A61P25/16; A61P25/28; A61P29/00; A61P43/00; C07K14/00; C07K14/50; C12N1/21; C12N15/18; C12N15/71; C12P21/02; A61K38/00; A61P9/00; C12R1/19

Domestic Patent References:

JP63500843A

Foreign References:

WO1990002800A1

Attorney, Agent or Firm:

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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