Title:
カリウムイブプロフェンの高度に濃厚な注入可能水溶液、それらの調製及びそれらの使用
Document Type and Number:
Japanese Patent JP2007515487
Kind Code:
A
Abstract:
Concentrated pourable potassium ibuprofen liquid compositions and their preparation are described. They are comprised of (i) potassium ibuprofen, (ii) water; and (iii) methanol, ethanol, 1-propanol, 2-propanol, 1,1-dimethylethanol, or a mixture of any two or more of them. The amount of dissolved potassium ibuprofen in the composition is in the range of about 60 to about 90 wt%. These compositions are suitable for use in the preparation of pharmaceutical dosage forms such as liquid-filled soft gelatin capsules, syrups, elixirs, suspensions; solid dosage forms such as tablets or caplets; and topically-applied products such as lotions, creams or ointments.
Inventors:
Phu, Patrick Sea
Lambeth, Gregory H.
Malcolm, Arsero Jei
Lambeth, Gregory H.
Malcolm, Arsero Jei
Application Number:
JP2006547093A
Publication Date:
June 14, 2007
Filing Date:
December 13, 2004
Export Citation:
Assignee:
Albemarle Corporation
International Classes:
A61K31/192; A61K9/08; A61K9/48; A61K9/66; A61K31/19; A61K47/10; A61K47/14; A61K47/34; A61P29/00
Domestic Patent References:
| JPH05310566A | 1993-11-22 | |||
| JPH01502185A | 1989-08-03 | |||
| JPH03502800A | 1991-06-27 |
Foreign References:
| WO2003075909A1 | 2003-09-18 |
Attorney, Agent or Firm:
Heikichi Odashima