Title:
高度に架橋しかつ極度に疎水性の酸化窒素放出性ポリマー及びその製造方法と用途
Document Type and Number:
Japanese Patent JP4796262
Kind Code:
B2
Abstract:
Extremely hydrophobic nitric oxide (NO) releasing polymers are disclosed. The extremely hydrophobic NO-releasing polymers provided are extensively cross-linked polyamine-derivatized divinylbenzene diazeniumdiolates. These polymers can be loaded with extremely high NO levels and designed to release NO in manners than mimic natural biological systems. The NO-releasing extremely hydrophobic polymers provided can maintain a sustained NO release for periods exceeding nine months. Also provided are related medical devices made using these NO-releasing extremely hydrophobic polymers.
Inventors:
Anthony El Fitzhue
Robert Caferate
Larry Kay Kiefer
Robert Caferate
Larry Kay Kiefer
Application Number:
JP2002292578A
Publication Date:
October 19, 2011
Filing Date:
October 04, 2002
Export Citation:
Assignee:
Medtronic Vascular Inc.
International Classes:
A61F13/15; C08F8/30; A61F2/82; A61F13/472; A61K31/785; A61K33/00; A61K47/48; A61L15/44; A61L17/14; A61L27/00; A61L27/34; A61L29/00; A61L29/08; A61L31/00; A61L31/10; A61M25/01; A61P7/02; A61P9/00; A61P9/10; A61P9/12; A61P15/10; A61P31/04; A61P35/00; A61P43/00
Domestic Patent References:
| JP10502905A |
Other References:
Huiping Zhang, Mark H. Schoenfisch, and Mark E. Meyerhoff,'Synthesis of Nitoric Oxide Releasing Silicone Rubbers for Biomedical Applications',Polym. Prepr.,1999年,Vol.40, No.2,pp.799-800
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Takashi Nakata
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Takashi Nakata