HIGHLY PRODUCTIVE MECHANISM FOR PRODUCING RECOMBINANT VIRUS BY USING SITE-SPECIFIC RECOMBINATION

Title:

HIGHLY PRODUCTIVE MECHANISM FOR PRODUCING RECOMBINANT VIRUS BY USING SITE-SPECIFIC RECOMBINATION

Document Type and Number:

Japanese Patent JP2010207231

Kind Code:

A

Abstract:

To provide a method for preparing a recombinant virus by using a site-specific recombination at the outside of a living body.

This method for performing the site-specific recombination includes: digesting a ring-formed virus genome DNA by a restriction enzyme to form a linear virus genome DNA which is adjacent to the site-specific recombinant site, and performing the site-specific recombination by using a desired genome material which is adjacent to the site-specific recombination site at the outside of the living body. Since the mixture obtained by performing the site-specific recombination can be applied to a host without having a further process such as the selection of a desired recombinant virus genome DNA, it is possible to obtain many recombinant viruses at the same time more quickly.

Inventors:

SON HO-SUN
KIM DO HUI
JUNG NEON-C
CHOI EUN-WOOK
SEEN DONG-SEUNG
KIM MIN SEONG
YI YONG-WEON
KIM KYUNG-JIN

Application Number:

JP2010094517A

Publication Date:

September 24, 2010

Filing Date:

April 15, 2010

Export Citation:

Click for automatic bibliography generation Help

Assignee:

BRN SCIENCE CO LTD

International Classes:

C12N15/09; C12N7/00; C12N7/01; C12N15/10; C12N15/63; C12N15/86; C12N15/866; C12Q1/68

Attorney, Agent or Firm:

Kenzo Hara International Patent Office

Previous Patent: METHOD FOR IDENTIFICATION, ASSESSMENT, AND TREATMENT OF PATIENT WITH PROTEASOME INHIBITION THERAPY

Next Patent: MODULATION OF GLUCOCORTICOID RECEPTOR EXPRESSION