Title:
ヒストンデアセチラーゼ阻害剤
Document Type and Number:
Japanese Patent JP2020504726
Kind Code:
A
Abstract:
本明細書では、ヒストンデアセチラーゼ（「ＨＤＡＣ」）酵素（例えば、ＨＤＡＣ１、ＨＤＡＣ２、およびＨＤＡＣ３）を阻害するための化合物および方法が提供される。
Inventors:
Luteke, gregory
Bagwat, Shri Pad
Bagwat, Shri Pad
Application Number:
JP2019533198A
Publication Date:
February 13, 2020
Filing Date:
December 22, 2017
Export Citation:
Assignee:
Biomarine Pharmaceutical Incorporated
International Classes:
C07D205/04; A61K31/397; A61K31/40; A61K31/438; A61K31/445; A61K31/4453; A61K31/451; A61K31/495; A61K31/551; A61P3/00; A61P21/00; A61P25/00; A61P25/02; A61P25/14; A61P25/28; A61P29/00; A61P31/00; A61P43/00; C07D207/09; C07D211/14; C07D211/22; C07D211/34; C07D221/20; C07D241/04; C07D243/08; C07D295/155; C07D487/10; C07D491/107; C12N9/99
Domestic Patent References:
| JP2009516743A | 2009-04-23 | |||
| JP2016520523A | 2016-07-14 | |||
| JP2005508905A | 2005-04-07 | |||
| JP2009501236A | 2009-01-15 | |||
| JP2009536615A | 2009-10-15 | |||
| JP2010531359A | 2010-09-24 |
Other References:
YOUNG, JUN SEO ET AL.: "Image-Guided Synthesis Reveals Potent Blood-Brain Barrier Permeable Histone Deacetylase Inhibitors", ACS CHEMICAL NEUROSCIENCE, vol. 5(7), JPN6021047896, 2014, pages 588 - 596, ISSN: 0004656964
Attorney, Agent or Firm:
Mizuno Yuuki
Etsu Tamai
Etsu Tamai