Title:
HOMINIZED ANTIBODY
Document Type and Number:
Japanese Patent JP3565572
Kind Code:
B2
Abstract:
PURPOSE: To obtain the novel antibody useful as an anti-tumor agent, etc.
CONSTITUTION: A hominized antibody reacting with ganglioside GM2, e.g. antibody KM966. The transformant KM966 (FERN BP-3931) expresses the exemplified antibody, which is useful for the diagnosis and therapy of cerebral tumor, peripheral nerve system tumor and lung cancer, etc.
Inventors:
Kazuyasu Nakamura
Masamichi Koike
Kenya Shitara
Cheno Hanai
Yoshitoshi Kuwana
Mamoru Hasegawa
Masamichi Koike
Kenya Shitara
Cheno Hanai
Yoshitoshi Kuwana
Mamoru Hasegawa
Application Number:
JP22143293A
Publication Date:
September 15, 2004
Filing Date:
September 06, 1993
Export Citation:
Assignee:
Kyowa Fermentation Industry Co., Ltd.
International Classes:
A61K39/395; A61P35/00; C07K16/18; C12N5/10; C12N15/02; C12N15/09; C12P21/08; C12N15/13; C12N15/62; C12R1/91; (IPC1-7): C07K16/18; A61K39/395; A61P35/00; C12N5/10; C12N15/02; C12N15/09; C12P21/08
Domestic Patent References:
| JP61047500A |
Other References:
J.Biol.Chem.,1989,Vol.264,No.21,p.12122-12125
Lancet,1989,Vol.1,No.8641,p.786-787
Nature,1988,Vol.332,No.24,p.323-327
Lancet,1989,Vol.1,No.8641,p.786-787
Nature,1988,Vol.332,No.24,p.323-327