Title:
植物源からカロテノイドを単離する方法
Document Type and Number:
Japanese Patent JP5794605
Kind Code:
B2
Abstract:
The present invention relates to a process for the isolation of carotenoid crystals having lutein and zeaxanthin in a weight ratio of 10:1, 5:1 and 1:1, respectively. The process comprises contacting a plant source rich in lutein with hexane and extracting at a temperature of 40°C to 60°C to obtain an oleoresin rich in lutein; contacting a plant source rich in zeaxanthin with hexane and extracting at a temperature of 40°C to 60°C to obtain an oleoresin rich in zeaxanthin. The oleoresin rich in lutein and the oleoresin rich in zeaxanthin are mixed separately in a ratios ranging from 80:20(w/w) to 90:10(w/w) or 70:30(w/w) to 30:70(w/w) or 10:90(w/w) to 20:80(w/w), respectively, and homogenized to obtain a mixed oleoresin. The mixed oleoresin is hydrolyzed with an alcoholic alkali at a temperature of 70°C to 80°C to obtain a reaction mixture. The carotenoid crystals are precipitated by adding hot water to the reaction mixture to form a precipitate. Carotenoid crystals having lutein and zeaxanthin in a weight ratio of 10:1 or 5:1 or 1:1, respectively, are obtained by filtering, washing, and drying the precipitate.
Inventors:
Ceslaman, Swaminathan
Madavarapir, Kunhiraman, Priya
Madavarapir, Kunhiraman, Priya
Application Number:
JP2010094863A
Publication Date:
October 14, 2015
Filing Date:
April 16, 2010
Export Citation:
Assignee:
Katra Phytochem (India) Private Limited
International Classes:
C07C403/08; A61K31/047; A61K36/28; A61K36/81; A61P3/02; A61P3/06; A61P9/10; A61P27/02; A61P37/02; A61P39/06
Domestic Patent References:
| JP2008538697A | ||||
| JP2005536547A | ||||
| JP2005511003A | ||||
| JP11322708A |
Foreign References:
| US20070032683 | ||||
| WO2007098520A1 |
Attorney, Agent or Firm:
Yuji Iwahashi