Title:
癌転移を処置するためにキナーゼを標的とする方法
Document Type and Number:
Japanese Patent JP2020530467
Kind Code:
A
Abstract:
本明細書において、インビボキナーゼスクリーニングによって同定された転移促進キナーゼを標的としたキナーゼ阻害剤を投与することによる、脳転移を処置するための方法を提供する。
Inventors:
Udifa
Lowry Frank
Jang Chang Yu
Acharya Sunil
Re-pin
Lowry Frank
Jang Chang Yu
Acharya Sunil
Re-pin
Application Number:
JP2020507545A
Publication Date:
October 22, 2020
Filing Date:
August 10, 2018
Export Citation:
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
International Classes:
A61K45/00; A61K31/12; A61K31/133; A61K31/137; A61K31/353; A61K31/404; A61K31/44; A61K31/444; A61K31/47; A61K31/4709; A61K31/472; A61K31/4741; A61K31/505; A61K31/506; A61K31/517; A61K31/519; A61K31/52; A61K31/5377; A61K31/55; A61K31/7105; A61K31/713; A61K31/7135; A61K45/06; A61K48/00; A61P11/00; A61P15/00; A61P25/00; A61P35/00; A61P35/04; A61P43/00
Domestic Patent References:
| JP2013231048A | 2013-11-14 | |||
| JP2008528001A | 2008-07-31 |
Foreign References:
| US20160008366A1 | 2016-01-14 |
Other References:
LOWERY,F.J.: "In Vivo Kinome Screen Reveals Non-canonical CDK-driven Metabolic Adaptation in Brain Metastasis.", THE UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER UTHEALTH GRADUATE SCHOOL OF BIOMEDICAL SCIENCES DI, JPN6022035153, 2016, pages 60 - 75, ISSN: 0005013825
STEM CELLS, vol. 35, JPN6022035152, June 2017 (2017-06-01), pages 1898 - 1912, ISSN: 0004856378
STEM CELLS, vol. 35, JPN6022035152, June 2017 (2017-06-01), pages 1898 - 1912, ISSN: 0004856378
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto