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Title:
How to analyze the cell or another biomechanical material containing nucleic acid
Document Type and Number:
Japanese Patent JP6033767
Kind Code:
B2
Abstract:
According to the invention there is provided a compound of Formula (I) in which: A is a C 2-8 alkylene group; R 1 , R 2 , R 3 , and R 4 are independently selected from hydrogen, C 1-4 alkyl, C 2-4 dihydroxyalkyl in which the carbon atom attached to the nitrogen atom does not carry a hydroxyl group and no carbon atom is substituted by two hydroxyl groups, or R 2 and R 3 together form a C 2-6 alkylene group which with the nitrogen atom to which R 2 and R 3 are attached forms a heterocyclic ring; X 1 , X 2 and X 3 are independently selected from hydrogen, hydroxyl, NR 1 -A-NR 2 R 3 R 4+ (Z m- ) 1/m , halogeno amino, C 1-4 alkoxy or C 2-8 alkanoyloxy; and (Z m- ) 1/m is an anion of charge m; or a derivative in which the group NR 1 is quaternarised.

Inventors:
Paul James Smith
Rachel Jay Ellington
Lawrence Hilton Patterson
Application Number:
JP2013503178A
Publication Date:
November 30, 2016
Filing Date:
April 08, 2011
Export Citation:
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Assignee:
Bio Status Limited
International Classes:
C07C225/34; C07C221/00; C07C225/36; C12Q1/04; C12Q1/68
Domestic Patent References:
JP4136802A
JP55029793A
JP50003337B1
JP2002531587A
JP52114784A
JP9118832A
JP2002539259A
Foreign References:
US3467483
US3646072
GB939513A
US3442895
WO2004060061A1
Other References:
Murdock, K. C. et al.,Antitumor Agents 1. 1,4-Bis[(aminoalkyl)amino]-9,10-anthracenediones,Journal of Medicinal Chemistry,1979年 1月 1日,vol.22 no.9,p.1024-1030
市川光男ほか,1,4-ビス(置換アミノ)- および 1-(置換アミノ)-4-オキシアントラキノン系カチオン染料合成,工業化学雑誌,1964年,vol.67 no.1,p.138-142
市川光男ほか,1-置換アミノ-, ならびに 1,5- および 1,8-ビス(置換アミノ)アントラキノン系カチオン染料の合成,工業化学雑誌,1964年,vol.67 no.1,p.142-145
N. P. Dhammika Nanayakkara et al.,Synthesis of water-soluble 9,10-anthraquinone analogues with potent cyanobactericidal activity toward the musty-odor cyanobacterium oscillatoria,Journal of Agricultural and Food Chemistry,2008年 2月 1日,vol.56 no.3,p.1002-1007
Biggerstaff J. P. et al.,New methodology for viability testing in environmetal samples,Molecular and Cellular Probes,2006年 4月 1日,vol.20 no.2,p.141-146
Katzhendler J. et al.,Synthesis of aminoanthraquinone derivatives and their in vitro evaluation as potential anti-cancer drugs,European Journal of Medicinal Chemistry,1989年 1月 1日,vol.24 no.1,p.23-30
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro