Title:
METHODS FOR REDUCING CD36 EXPRESSION
Document Type and Number:
Japanese Patent JP2017066161
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a method for reducing CD36 expression in a cell.SOLUTION: The present invention provides a method comprising contacting a cell with an effective amount of an aromatic-cationic peptide having at least one net positive charge; a minimum of four amino acids; a maximum of about 20 amino acids; a relationship between the minimum number of net positive charges (p) and the total number of amino acid residues (r) in which 3 pm is the largest number that is less than or equal to r+1; and a relationship between the minimum number of aromatic groups (a) and the total number of net positive charges (p) in which 2a is the largest number that is less than or equal to pt+1, except that when a is 1, pmay also be 1.SELECTED DRAWING: None
Inventors:
SZETO HAZEL H
LIU SHAOYI
CHO SUNGHEE
LIU SHAOYI
CHO SUNGHEE
Application Number:
JP2017000444A
Publication Date:
April 06, 2017
Filing Date:
January 05, 2017
Export Citation:
Assignee:
CORNELL RES FOUNDATION INC
International Classes:
A61K38/00; A61K38/08; A61P3/10; A61P9/10; A61P13/02; A61P13/12; A61P25/28; A61P43/00
Domestic Patent References:
| JP2004035510A | 2004-02-05 | |||
| JP2015164953A | 2015-09-17 | |||
| JP2004035510A | 2004-02-05 | |||
| JP2015164953A | 2015-09-17 |
Foreign References:
| WO2005072295A2 | 2005-08-11 | |||
| WO2005072295A2 | 2005-08-11 |
Attorney, Agent or Firm:
Takaki Nishijima
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Toshio Takizawa
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Toshio Takizawa
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