光投影画像システム、および核を有する細胞および疾病に関与する細胞質密度の特徴を自動的に検出する方法

Japanese Patent JP2005539209

A

A system and method for rapidly detecting cells of interest using multi-dimensional, highly quantitative, nuclear and cytoplasmic densitometric features (NDFs and CDFs) includes a flow optical tomography (FOT) instrument capable of generating various optical projection images (or shadowgrams) containing accurate density information from a cell, a computer and software to analyze and reconstruct the projection images into a multi-dimensional data set, and automated feature collection and object classifiers. The system and method are particularly useful in the early detection of cancers such as lung cancer using a bronchial specimen from sputum or cheek scrapings and cervical/ovarian cancer using a cervical scraping, and the system can be used to detect rare cells in specimens including blood.

JPWO2005111587	Biological sample detector
JP4262559	Electrophoresis analyzer
JP2001052232	PAPER SHEET GENUINE/FALSE DISCRIMINATION DEVICE

Nelson, Alan, Sea.

JP2003561404A

December 22, 2005

January 21, 2003

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Vision Gate, Incorporated

G01N21/64; C12Q1/04; G01N15/14; G01N21/00; G01N21/17; G01N21/78; G01N23/04; G01N33/48; G01N33/487; G01N33/50; G01N33/543; G01N33/554; G01N33/60; G03C3/00; G06F15/00; G06F19/00; G06K9/00; G06T1/00; G06T3/00; G06T7/00; G06T11/00; G01N21/05; A61B; (IPC1-7): G01N33/48; C12Q1/04; G01N21/17; G01N21/64; G01N33/50

JPH0579970A	1993-03-30
JPS63168562A	1988-07-12
JPH05346391A	1993-12-27
JPH0579971A	1993-03-30
JPH0472544A	1992-03-06
JPH01219654A	1989-09-01
JP2001174456A	2001-06-29
JPH02203246A	1990-08-13
JPS6468638A	1989-03-14

Masao Okabe
Nobuaki Kato
Kazuo
Shinichi Usui
Takao Ochi
Teruhisa Motomiya
Asahi Shinmitsu
Katsumi Miyama

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