Title:
菊酸のエナンチオマーの取得方法
Document Type and Number:
Japanese Patent JP5043685
Kind Code:
B2
Abstract:
A new process is described, easy to perform on industrial scale, with high yield, for obtaining enantiomers of chrysanthemic acid starting from mixtures containing them. The process involves reacting said mixtures with enantiomers of 2- dimethylamino-1-phenyl-1 ,3-propanediol (DMPP) and 2-dimethylamino-1-[4- (methylthio)phenyl]propane-1 ,3-diol (MTDP) as chiral selectors. The invention includes salts of chrysanthemic acid with the aforesaid chiral selectors as process intermediates. The process allows operation in a single solvent rather than in solvent mixtures difficult to recover and reuse, and the final crystallization product does not incorporate molecules of solvent. The bases used are then recovered and reused in subsequent separations.
Inventors:
Bolzzatta Valerio
Rossini Goffredo
Ayoub Claudia
Liji Paolo
Capparella Elisa
Rossini Goffredo
Ayoub Claudia
Liji Paolo
Capparella Elisa
Application Number:
JP2007555613A
Publication Date:
October 10, 2012
Filing Date:
February 16, 2006
Export Citation:
Assignee:
ENDURA S.P.A.
International Classes:
C07C51/487; C07C61/37; C07C323/32; C07B57/00
Domestic Patent References:
| JP2002326971A | ||||
| JP2001114728A | ||||
| JP11217354A | ||||
| JP61172853A | ||||
| JP2000134A | ||||
| JP55154938A | ||||
| JP1022837A | ||||
| JP57197242A |
Attorney, Agent or Firm:
Michio Nagai
Yoichi Iino
Yoichi Iino