Title:
シームレスカプセルの製造方法
Document Type and Number:
Japanese Patent JP4778639
Kind Code:
B2
Abstract:
Disclosed is a seamless capsule manufacturing method formed by encapsulating a filler material with a capsule shell material, said method comprising: a step of preparing a concentric multiple nozzle having a center nozzle and an annular nozzle concentrically surrounding the center nozzle; a step of preparing a tubular member in which a curing liquid for curing a liquid capsule shell material by coming into contact with the capsule shell material flows, and said tubular member having a vertical portion which extends vertically and has an open upper end; a step of supplying a liquid filler material to the center nozzle of the concentric multiple nozzle, and supplying a liquid capsule shell material to the annular nozzle of the concentric multiple nozzle; a step of forming a concentric columnar composite flow which includes the flow of the liquid filler material discharged from the center nozzle and the flow of the liquid capsule shell material discharged from the annular nozzle and flowing around the flow of the filler material, and cutting the composite flow from the end thereof to form a droplet; and a step of introducing the droplet into the curing liquid in the vertical portion of the tubular member such that the position of introduction is misaligned relative to the center of the vertical portion, and curing the capsule shell material of the droplet by coming into contact with the curing liquid.
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Inventors:
Rei Nakajima
Masayoshi Yamazaki
Takeshi Nakamura
Yamamoto Tsukasa
Masayoshi Yamazaki
Takeshi Nakamura
Yamamoto Tsukasa
Application Number:
JP2001246899A
Publication Date:
September 21, 2011
Filing Date:
August 16, 2001
Export Citation:
Assignee:
Chugai Pharmaceutical Co., Ltd.
International Classes:
A61J3/07; A61K9/48; A61K9/50; B01J13/14
Domestic Patent References:
| JP2122827A | ||||
| JP9155183A | ||||
| JP5138012A | ||||
| JP59112833A | ||||
| JP50030781A | ||||
| JP8010313A |
Attorney, Agent or Firm:
Yoshiki Hasegawa
Yoshinori Shimizu
Toru Suganuma
Yoshinori Shimizu
Toru Suganuma