Title:
シクロヘプテノン誘導体及びその製造方法並びにそれを利用してシクロヘプトイミダゾール誘導体を製造する方法
Document Type and Number:
Japanese Patent JP4018816
Kind Code:
B2
Abstract:
The present invention relates to compounds of formula (1).wherein: R1 is hydrogen atom or lower alkyl group, X is bromine atom or chlorine atom; and which are useful for the preparation of the cycloheptanoides such as cycloheptimidazole derivatives. The compound having formula (1) is obtained in a single pot by the reaction of a trialkylsilylether compound with a dihalocarbene which, in turn, is prepared from the reaction of chloroform or bromoform in the presence of base.
Inventors:
Go Tomiyama
Tomiyama
Naoto Ueyama
Akira Ohno
Tomiyama
Naoto Ueyama
Akira Ohno
Application Number:
JP25359598A
Publication Date:
December 05, 2007
Filing Date:
September 08, 1998
Export Citation:
Assignee:
Toh Pharmaceutical Co., Ltd.
International Classes:
A61P9/10; C07C49/717; A61P9/12; C07C45/51; C07C45/52; C07C45/71; C07C49/753; C07D235/02
Domestic Patent References:
JP62093250A | ||||
JP59219246A |
Foreign References:
US3658841 |
Attorney, Agent or Firm:
Hiroshi Tanaka
Eishiro Higuchi
Eishiro Higuchi