Title:
【発明の名称】医療用途を有する新規なヘミン錯化合物を製造する方法
Document Type and Number:
Japanese Patent JPH0647541
Kind Code:
B2
Abstract:
A method for the preparation of a new, physiologically active, water-soluble complex compound of hemin arginate or hemin lysinate in which crystalline hemin and the amino acid L-arginine or L-lysine, in a molar proportion of 1:3, are allowed to react at room temperature under vigorous stirring for 10 to 15 hours in a solvent mixture of acetone and water 300:20 v/v. The hemin arginate or hemin lysinate thus formed is a powdery, stable compound suitable for use as raw material in tablets or capsules or as dry substance for preparation of injections for treatment of various types of anemia, particularly anemias associated with prophyria.
Inventors:
GURERUSU DANIERU INGUBERUGU
RITOBA REIRA ANERI PENTEIRE
RAINO ORABI TOKORA
RAIMO ANTERO TENHAUNEN
RITOBA REIRA ANERI PENTEIRE
RAINO ORABI TOKORA
RAIMO ANTERO TENHAUNEN
Application Number:
JP930285A
Publication Date:
June 22, 1994
Filing Date:
January 23, 1985
Export Citation:
Assignee:
MEDEIKA AB OY
International Classes:
A61K31/555; A61K9/08; A61K9/14; A61K9/19; A61K35/14; A61K47/18; A61P7/06; C07D487/22; C07F15/02; C07H23/00; A61K31/40; (IPC1-7): A61K31/555; A61K47/18
Domestic Patent References:
| JP559023A | ||||
| JP5780317A | ||||
| JP57209211A | ||||
| JP4930521A |
Attorney, Agent or Firm:
Toda Chikio
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