Title:
間葉系幹細胞から軟骨細胞を調製する方法
Document Type and Number:
Japanese Patent JP4929447
Kind Code:
B2
Abstract:
To provide a method for differentiation-inducing mesenchymal stem cells having pluripotency to the chondrocytes.
The invention relates to the method for preparing the chondrocytes from the mesenchymal stem cells by cultivation in a medium free from non-peptide differentiation inducing factor. The chondrocytes prepared by the method excludes polypeptide differentiation inducing factors as foreign substances, capable of avoiding problems such as adverse effects in grafting, easy to culture and reducing the preparation cost.
COPYRIGHT: (C)2007,JPO&INPIT
Inventors:
Masaru Tanaka
Morita Yuka
Sadaaki Yamamoto
Masatsugu Shimomura
Morita Yuka
Sadaaki Yamamoto
Masatsugu Shimomura
Application Number:
JP2005143162A
Publication Date:
May 09, 2012
Filing Date:
May 16, 2005
Export Citation:
Assignee:
National University Corporation Hokkaido University
International Classes:
C12N5/077; A61L27/00; C12N5/07; C12N5/074; C12N5/0775; C12N15/09
Domestic Patent References:
| JP2005080599A |
Other References:
Bone, 35[4](2004) p.850-858
Osteoarthritis and Cartilage, 11[1](2003) p.55-64
Tissue Eng., 9[4](2003) p.679-688
Osteoarthritis and Cartilage, 12[10](2004) p.834-842
Biochem. Biophys. Res. Commun., 320[3](2004) p.914-919
Osteoarthritis and Cartilage, 11[1](2003) p.55-64
Tissue Eng., 9[4](2003) p.679-688
Osteoarthritis and Cartilage, 12[10](2004) p.834-842
Biochem. Biophys. Res. Commun., 320[3](2004) p.914-919
Attorney, Agent or Firm:
Koichi Washida
Kazuto Iinuma
Kazuto Iinuma