Title:
How to produce the modulator of a cystic fibrosis membrane conductance control agent
Document Type and Number:
Japanese Patent JP5976088
Kind Code:
B2
Abstract:
The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 2; in the presence of a coupling agent.
Inventors:
John DeMattery
Adam Earl. Rooker
Bobbiana Neubert-Rangil
Martin Trudeau
Stephanie roper
Michael P. Ryan
Darika Milfred Lao Yap
Brian Earl. Kruger
Peter Day Y. Gluten Huis
Frederick F. Fan Goor
Martin Sea. Botfield
Gregor Zrocarnik
Adam Earl. Rooker
Bobbiana Neubert-Rangil
Martin Trudeau
Stephanie roper
Michael P. Ryan
Darika Milfred Lao Yap
Brian Earl. Kruger
Peter Day Y. Gluten Huis
Frederick F. Fan Goor
Martin Sea. Botfield
Gregor Zrocarnik
Application Number:
JP2014255432A
Publication Date:
August 23, 2016
Filing Date:
December 17, 2014
Export Citation:
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
C07D215/56; C07C219/34
Domestic Patent References:
| JP2008504291A |
Foreign References:
| WO2007134279A2 | ||||
| WO2007079139A2 | ||||
| WO2007106537A2 | ||||
| WO2007124318A1 | ||||
| WO2009036412A1 |
Other References:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2009年 2月 8日,V19,P1584-1587
CHEMICAL AND PHARMACEUTICAL BULLETIN,1976年,V24,P130-135
CHEMICAL AND PHARMACEUTICAL BULLETIN,1990年,V38 N11,P2919-2925
JOURNAL OF MEDICINAL CHEMISTRY,1993年,V36,P2801-2809
HETEROCYCLES,2003年,V60 N4,P833-842
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2003年,V125 N37,P11176-11177
CHEMICAL AND PHARMACEUTICAL BULLETIN,1976年,V24,P130-135
CHEMICAL AND PHARMACEUTICAL BULLETIN,1990年,V38 N11,P2919-2925
JOURNAL OF MEDICINAL CHEMISTRY,1993年,V36,P2801-2809
HETEROCYCLES,2003年,V60 N4,P833-842
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2003年,V125 N37,P11176-11177
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita