Title:
血管新生を減少させる方法
Document Type and Number:
Japanese Patent JP4494793
Kind Code:
B2
Abstract:
The present invention provides methods of reducing angiogenesis in an individual. The methods generally involve administering to the individual an effective amount of a nicotinic acetyl choline receptor antagonist. The methods are useful to treat conditions associated with or resulting from angiogenesis, particularly pathological angiogenesis. The invention further provides methods of treating a condition associated with or resulting from angiogenesis.
Inventors:
Kooke John
Hetzen Christopher
Weiss Michael
Hetzen Christopher
Weiss Michael
Application Number:
JP2003567390A
Publication Date:
June 30, 2010
Filing Date:
February 04, 2003
Export Citation:
Assignee:
The Board of Trustees of the Leland Stanford Junior University
International Classes:
A61K31/13; A61K45/00; A61K31/00; A61K31/14; A61K31/225; A61K31/40; A61K31/403; A61K31/4188; A61K31/445; A61K31/4745; A61K45/06; A61P9/00; A61P19/02; A61P27/02; A61P35/00; A61P43/00
Foreign References:
| WO2000035279A1 | ||||
| WO2000054762A1 |
Other References:
VILLABLANCA,A.C.,Nicotine stimulates DNA synthesis and proliferation in vascular endothelial cells in vitro,J Appl Physiol,1998年,Vol.84, No.6,p.2089-98
Rhoda Maneckjee. et al,Aanalgesia,1995年,Vol.1, No.4-6,p.548-52
Rhoda Maneckjee. et al,Aanalgesia,1995年,Vol.1, No.4-6,p.548-52
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Kazuya Kawamoto