Title:
ペルゴリドの合成方法
Document Type and Number:
Japanese Patent JP2005520833
Kind Code:
A
Abstract:
A process for the synthesis of pergolide (Formula (I)) (D-6-n-propyl-8betamethylmercaptomethylergo line) from acid 9,10-dihydrolysergic is herein disclosed. The process can be carried out without isolating most intermediates and is particularly convenient both from the yield and safety standpoint. Moreover, pergolide thereby obtained is highly pure and can be conveniently transformed into pergolide mesylate
Inventors:
Fog, Walter
Paisoni, Paolo
Loretto, Jacopo
Fonte, Piera
Ormo, Sara
Paisoni, Paolo
Loretto, Jacopo
Fonte, Piera
Ormo, Sara
Application Number:
JP2003576437A
Publication Date:
July 14, 2005
Filing Date:
March 10, 2003
Export Citation:
Assignee:
ANTIBIOTICOS S.p.A.
International Classes:
C07D471/04; C07D457/02; C07D457/04; (IPC1-7): C07D471/04
Attorney, Agent or Firm:
Akio Miyazaki
Katsuhiro Ito
Ishibashi Masayuki
Katsuhiro Ito
Ishibashi Masayuki