Title:
スフィンゴシンの合成方法
Document Type and Number:
Japanese Patent JP4282981
Kind Code:
B2
Abstract:
This invention relates to a method for the production of a sphingoid base according to formulacomprising the steps of(1) dissolving a starting compound according to formula III or a salt thereof in a substantially inert solvent,(2) protecting the NH2 group with a NH2 protecting group,(3) activating the C-4 HR<3 >group for an elimination reaction with the C-5 HR<4 >group,(4) causing an elimination reaction to take place to form a double bond between the C-4 and C-5 carbon atom, and(5) removing the NH2 protecting group.
Inventors:
Van Boom, Jacobs Hubertus
Van den berg, richard
Van den berg, richard
Application Number:
JP2002369986A
Publication Date:
June 24, 2009
Filing Date:
December 20, 2002
Export Citation:
Assignee:
Cosmoferm B. buoy.
International Classes:
C07C213/08; C07D263/14; C07C215/24; C07C247/04; C07C247/08; C07D413/04; C07F7/08
Domestic Patent References:
| JP7291904A | ||||
| JP7258178A | ||||
| JP9503786A | ||||
| JP5025103A | ||||
| JP62207247A | ||||
| JP63277641A |
Attorney, Agent or Firm:
Yoshiyuki Inaba
Katsuro Tanaka
Shinji Oga
Katsuro Tanaka
Shinji Oga