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Title:
アリール-シクロプロピル誘導体のアスパルチルプロテアーゼ阻害剤を使用してアミロイドーシスを治療する方法
Document Type and Number:
Japanese Patent JP2009511589
Kind Code:
A
Abstract:
The invention relates to novel compounds and methods of treating diseases, disorders, and conditions associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.

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Inventors:
Hom, Roy
Toss, gargerie
Probst, Garry
Bowers, Simion
Truong, An
Tongue, Jay S
Nates, Earl Jeffrey
Application Number:
JP2008535650A
Publication Date:
March 19, 2009
Filing Date:
October 11, 2006
Export Citation:
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Assignee:
Elan Pharmaceuticals, Inc.
International Classes:
C07C233/36; A61K31/164; A61K31/341; A61K31/351; A61K31/357; A61K31/381; A61K31/407; A61K31/415; A61K31/4155; A61K31/4192; A61K31/42; A61K31/426; A61K31/4418; A61K31/5377; A61K31/54; A61K31/553; A61P25/28; A61P43/00; C07C323/32; C07D213/42; C07D231/12; C07D249/04; C07D261/08; C07D265/32; C07D267/08; C07D277/28; C07D295/12; C07D307/14; C07D309/20; C07D317/28; C07D319/12; C07D321/06; C07D333/20; C07D403/12; C07D405/10; C07D409/04; C07D409/06; C07D413/12; C07D491/048
Attorney, Agent or Firm:
Shinjiro Ono
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Norihiro Fukasawa