Title:
How to treat or prevent diseases of the nervous system
Document Type and Number:
Japanese Patent JP6184942
Kind Code:
B2
Abstract:
The present disclosure provides a method for treating an inflammatory neurological disease comprising administering a population of cells enriched for STRO-1+ cells and/or progeny thereof and/or soluble factors derived therefrom.
Inventors:
Claude Bernard
Application Number:
JP2014513004A
Publication Date:
August 23, 2017
Filing Date:
June 04, 2012
Export Citation:
Assignee:
Mesoblast, Incorporated
International Classes:
A61P21/04; A61K35/28; A61P25/00; A61P29/00; A61P37/02; A61P37/06
Domestic Patent References:
| JP2007535302A | ||||
| JP2008543340A |
Foreign References:
| WO2010057260A1 |
Other References:
UCCELLI, A. and PROCKOP, D.J.,Why should mesenchymal stem cells (MSCs) cure autoimmune diseases?,Curr Opin Immunol,2010年,Vol.22, No.6,p.768-74,ISSN 0952-7915
ZAPPIA, E. et al.,Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy,Blood,2005年,Vol.106, No.5,p.1755-61,ISSN 0006-4971
ITESCU, S. et al.,Mesenchymal Progenitor Cells for Vascular Network Formation and Cardicac Muscle Regeneration,STEM CELLS AND MYOCARDIAL REGENERATION , Edited by PENN, M.S.,Totowa, New Jersey: Humana Press,2007年,p.57-66
FRANCOIS, S. et al.,Stro-1 Positive and Stro-1 Negative Human Mesenchymal Stem Cells Express Different Levels of Immunosuppression,Blood (ASH Annual Meetings Abstracts),2005年,Vol.106,p.2305,ISSN 0006-4971
NASEF, A. et al.,Selected Stro-1-enriched bone marrow stromal cells display a major suppressive effect on lymphocyte proliferation,Int J Lab Hematol,2009年,Vol.31, No.1,p.9-19,ISSN 1751-5521
HO, A.D. et al.,Heterogeneity of mesenchymal stromal cell preparations,Cytotherapy,2008年,Vol.10, No.4,p.320-30,ISSN 1465-3249
ZAPPIA, E. et al.,Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy,Blood,2005年,Vol.106, No.5,p.1755-61,ISSN 0006-4971
ITESCU, S. et al.,Mesenchymal Progenitor Cells for Vascular Network Formation and Cardicac Muscle Regeneration,STEM CELLS AND MYOCARDIAL REGENERATION , Edited by PENN, M.S.,Totowa, New Jersey: Humana Press,2007年,p.57-66
FRANCOIS, S. et al.,Stro-1 Positive and Stro-1 Negative Human Mesenchymal Stem Cells Express Different Levels of Immunosuppression,Blood (ASH Annual Meetings Abstracts),2005年,Vol.106,p.2305,ISSN 0006-4971
NASEF, A. et al.,Selected Stro-1-enriched bone marrow stromal cells display a major suppressive effect on lymphocyte proliferation,Int J Lab Hematol,2009年,Vol.31, No.1,p.9-19,ISSN 1751-5521
HO, A.D. et al.,Heterogeneity of mesenchymal stromal cell preparations,Cytotherapy,2008年,Vol.10, No.4,p.320-30,ISSN 1465-3249
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro