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Title:
ステロール吸収阻害剤を使用して血管炎症を治療または予防する方法
Document Type and Number:
Japanese Patent JP4395370
Kind Code:
B2
Abstract:
The present invention provides methods for treating or preventing vascular inflammation or for reducing blood levels of c-reactive protein by administering at least one sterol absorption inhibitor and/or at least one 5alpha-stanol absorption inhibitor.

Inventors:
Davis, Harry Earl.
Application Number:
JP2003530281A
Publication Date:
January 06, 2010
Filing Date:
September 19, 2002
Export Citation:
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Assignee:
Schering Corporation
International Classes:
A61K31/095; A61K31/015; A61K31/06; A61K31/16; A61K31/17; A61K31/18; A61K31/19; A61K31/192; A61K31/194; A61K31/195; A61K31/202; A61K31/216; A61K31/351; A61K31/355; A61K31/365; A61K31/366; A61K31/375; A61K31/397; A61K31/40; A61K31/404; A61K31/44; A61K31/4418; A61K31/444; A61K31/455; A61K31/496; A61K31/506; A61K31/56; A61K31/575; A61K31/675; A61K31/70; A61K31/7056; A61K31/7115; A61K31/714; A61K31/715; A61K31/74; A61K33/24; A61K45/00; A61K45/06; A61P9/00; A61P29/00; A61P43/00; C07D205/08; C07H17/02
Domestic Patent References:
JP8509989A
JP6508637A
Foreign References:
WO2002058696A1
Other References:
AMBROSI,P. et al, The best of 2001. Clinical pharmacology, Arch Mal Coeur Vaiss, 2002, Vol.95 Spec No 1, No.5 Spec 1, p.33-8
田中明, スタチンのHDLへの作用, Geriatric Medicine, April 2001, Vol.39, No.4, p.565-70
ROSENSON, R.S., Oxidative Stress an Inflammation: New Targets for Statin Therapy, March 2001, Vol.65, Suppl.1-A p.94
BAYS,H.E. et al, Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: pooled analysis of two phase II studies, Clin Ther, 2001, Vol.23, No.8, p.1209-30
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita