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Title:
血管疾患の治療方法
Document Type and Number:
Japanese Patent JP2005525848
Kind Code:
A
Abstract:
The present invention relates to a method of treating patients suffering from, or at risk for, intimal hyperplasia and/or arteriosclerosis. The treatment includes administering a pharmaceutical composition that includes carbon monoxide to the patient.

Inventors:
Otterbane Leo E.
Choi Augustine M. K.
Bach Fritz H.
Zucker Brown Brian
Application Number:
JP2003570771A
Publication Date:
September 02, 2005
Filing Date:
February 13, 2003
Export Citation:
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Assignee:
Beth Israel Decones Medical Center
University of Pittsburgh of the Commonwealth System of Higher Education
International Classes:
A61B18/20; A61F2/82; A61F2/958; A61K33/00; A61M25/00; A61M25/10; A61P7/02; A61P9/10; A61P9/14; A61P41/00; (IPC1-7): A61M29/00; A61B18/20; A61K33/00; A61M25/00; A61M29/02; A61P7/02; A61P9/10; A61P9/14; A61P41/00
Domestic Patent References:
JP2001501612A2001-02-06
JPH0898893A1996-04-16
JP2001082698A2001-03-30
JP3019366U1995-12-12
JPH07500988A1995-02-02
JPH10501539A1998-02-10
JP2000517311A2000-12-26
JP2000037368A2000-02-08
Other References:
RANDA ZAKHARY, SEAN P. GAINE, JAY L. DINERMAN, MARTIAL RUAT, NICHOLAS A. FLAVAHAN,AND SOLOMON H. SNY: "Heme oxygenase 2: Endothelial and neuronal localization and rolein endothelium-dependent relaxation", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 93, JPN6009002856, January 1996 (1996-01-01), US, pages 795 - 798, ISSN: 0001234405
IVAN A. SAMMUT, ROBERTA FORESTI, JAMES E. CLARK, DAVID J. EXON, MARTIN J.J. VESELY, PADMINI SARATHCH: "Carbon monoxide is a major contributor to the regulation ofvascular tone in aortas expressing high l", BRITISH JOURNAL OF PHARMACOLOGY, vol. Vol.125(7), JPN6009002853, December 1998 (1998-12-01), GB, pages 1437 - 1444, ISSN: 0001234406
Attorney, Agent or Firm:
Hatsushi Shimizu
Kazunori Hashimoto
Koichi Niimi