Title:
ヒト細胞を若返らせるためのＺＳＣＡＮ４の使用方法
Document Type and Number:
Japanese Patent JP7331040
Kind Code:
B2
Abstract:
The present disclosure relates to methods for increasing telomere length in one or more human cells and/or increasing genome stability of one or more human cells, for example by contacting one or more human cells with an agent that increases expression of Zscan4 in the one or more human cells. Methods of treating a subject in need of telomere lengthening, treating a disease or condition associated with a genomic and/or chromosome abnormality, of rejuvenating one or more human cells, of rejuvenating tissues or organs, and of rejuvenating a subject in need thereof, for example by contacting one or more human cells in the subject with an agent that increases expression of Zscan4, or by administering to a subject in need thereof, an agent that increases expression of Zscan4 are also provided.
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Inventors:
Minoru S.H.Co
Application Number:
JP2021085867A
Publication Date:
August 22, 2023
Filing Date:
May 21, 2021
Export Citation:
Assignee:
Elixirgen Therapeutics, Inc.
International Classes:
A61K38/17; A61K31/7088; A61K31/7105; A61K35/12; A61K35/15; A61K35/28; A61K35/545; A61K35/76; A61K47/64; A61K48/00; A61P1/00; A61P3/10; A61P9/00; A61P11/00; A61P13/12; A61P15/00; A61P21/00; A61P25/00; A61P27/02; A61P27/16; A61P43/00
Domestic Patent References:
| JP2013503638A |
Foreign References:
| WO2012129342A1 |
Other References:
Aging Cell, 2007,Vol.6, No.3, pp.383-394
British Journal of Haematology, 1999, Vol.105, pp.883-893
British Journal of Haematology, 1999, Vol.105, pp.883-893
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Tatsunori Ikeda
Hidenao Tsuda
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Tatsunori Ikeda
Hidenao Tsuda