Title:
心血管状態の治療において脂肪組織由来細胞を使用する方法
Document Type and Number:
Japanese Patent JP5210155
Kind Code:
B2
Abstract:
Adipose derived regenerative cells are used to treat patients, including patients with cardiovascular conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells, e.g., stem and/or progenitor cells, obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, adipose derived regenerative cells are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic cardiovascular benefit.
Inventors:
Johun Kay. Frasel
Marc H. Hedrikuk
Min Zhu
Brian M. Strem
Eric Daniels
Isabel La Uluru
Marc H. Hedrikuk
Min Zhu
Brian M. Strem
Eric Daniels
Isabel La Uluru
Application Number:
JP2008513441A
Publication Date:
June 12, 2013
Filing Date:
May 25, 2005
Export Citation:
Assignee:
Site Res Therapeutics, Inc.
International Classes:
A61K35/12; A61K35/34; A61K45/00; A61P9/00; A61P9/02; C12N5/071; C12N5/0775
Domestic Patent References:
| JP2004532202A |
Foreign References:
| WO2003053346A1 | ||||
| WO2005034843A1 | ||||
| WO2005063967A1 |
Other References:
Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure,Circulation,2003年,Vol.107, No.18,p.2294-302
SAITO,T. et al,Transcoronary implantation of bone marrow stromal cells ameliorates cardiac function after myocardial infarction,The Journal of thoracic and cardiovascular surgery,2003年,Vol.126, No.1,p.114-23
PLANAT-BENARD,V. et al,Spontaneous cardiomyocyte differentiation from adipose tissue stroma cells,Circulation research,2004年,Vol.94, No.2,p.223-9
SAITO,T. et al,Transcoronary implantation of bone marrow stromal cells ameliorates cardiac function after myocardial infarction,The Journal of thoracic and cardiovascular surgery,2003年,Vol.126, No.1,p.114-23
PLANAT-BENARD,V. et al,Spontaneous cardiomyocyte differentiation from adipose tissue stroma cells,Circulation research,2004年,Vol.94, No.2,p.223-9
Attorney, Agent or Firm:
Toru Ishikawa